Prep the oven and pan: Preheat the oven to 375°F (190°C).
Line a 12-cup muffin pan with paper liners or lightly grease it.
Mix wet ingredients: In a large bowl, whisk the Greek yogurt, eggs, oil, sugar, vanilla, and lemon zest until smooth.
Combine dry ingredients: In a separate bowl, whisk the all-purpose flour, protein powder, baking powder, baking soda, and salt. This prevents clumps and helps even rise.
Bring the batter together: Add the dry mixture to the wet mixture. Stir gently with a spatula until just combined.
The batter should be thick but scoopable. Avoid overmixing.
Prep the blueberries: Toss the blueberries with 1 tablespoon of flour to help prevent sinking. Fold them into the batter carefully, saving a few to press on top of each muffin if you like a bakery look.
Fill the pan: Divide the batter evenly among 12 cups, filling each about 3/4 full.
Sprinkle with coarse sugar if using.
Bake: Bake for 16–20 minutes, or until the tops are set and lightly golden, and a toothpick comes out with a few moist crumbs. If you’re using frozen berries, tack on a minute or two.
Cool: Let muffins rest in the pan for 5 minutes, then transfer to a rack to cool completely. This keeps the bottoms from steaming and getting soggy.