Prep the chicken: Pat chicken dry with paper towels. In a bowl, whisk cornstarch, garlic powder, onion powder, salt, and pepper.
Add chicken and toss until every piece is lightly coated.
Preheat the air fryer: Set to 400°F (200°C) for 3–5 minutes. Lightly spray the basket with oil to prevent sticking.
Air-fry the chicken: Arrange chicken in a single layer without crowding. Lightly mist the tops with oil.
Air-fry 8–10 minutes, flipping halfway, until golden and cooked through (internal temp 165°F). Work in batches if needed for crispiness.
Make the orange sauce: While chicken cooks, whisk orange juice, zest, soy sauce, honey, vinegar, garlic, ginger, and red pepper flakes in a skillet over medium heat. Bring to a gentle simmer.
Thicken the sauce: Stir in the cornstarch slurry and simmer 1–2 minutes until glossy and slightly thick.
If too thick, add a splash of water. Remove from heat and stir in sesame oil.
Toss and serve: Add the crispy chicken to the skillet and toss until coated. Serve over rice with broccoli, then garnish with green onions and sesame seeds.